Butane

Butane

SCHEMBL8445223

CCCC.O=C1CCNC1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.34
GABRB2 P47870 2/20 0.34
MEN1 O00255 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
GMNN O75496 1/20 0.33
BLM P54132 1/20 0.33
CHRM3 P20309 2/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
CHRM1 P11229 1/20 0.32
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Heptane SCHEMBL28263405 0.89 ALOX5 (0.37) HSD17B10
SCHEMBL4298137 0.87
SCHEMBL11749187 0.87
SCHEMBL10715 0.87
Hydrochloric Acid SCHEMBL969582 0.84
Ethylene SCHEMBL4230122 0.81
Ethylene Glycol SCHEMBL28999587 0.80 GABRA1 (0.34) GABRA1GABRB2MEN1CYP2C19KMT2A
Acetic Acid SCHEMBL27720658 0.78 PNMT (0.38) GABRA1GABRB2MEN1CYP2C19KMT2A
Ethoxycarbonyl Group SCHEMBL27553044 0.78 CHRM3 (0.31) CHRM3
SCHEMBL31553570 0.76 CHRM3 (0.35) CYP2C19BLMCHRM3HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0934080-A2 1,3-BIS-(N-LACTAMYL) PROPANE AND THE PHARMACEUTICAL AND COSMETIC USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 1999-08-11 EP disclosed
WO-1998015291-A1 1,3-BIS-(N-LACTAMYL) PROPANE AND THE PHARMACEUTICAL AND COSMETIC USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 1998-04-16 WO disclosed