Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 8/20 | 0.38 |
| ▸ | CDK9 | P50750 | 8/20 | 0.38 |
| ▸ | MMP2 | P08253 | 5/20 | 0.38 |
| ▸ | MMP3 | P08254 | 5/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446917 | 0.83 | MEN1 (0.39) | CCNT1CDK9NAMPT | |
| SCHEMBL7514922 | 0.80 | NAMPT (0.48) | KITNAMPTWNT3A | |
| SCHEMBL7514921 | 0.79 | MAOA (0.49) | — | |
| SCHEMBL8451797 | 0.77 | MAPKAPK2 (0.39) | NAMPT | |
| SCHEMBL7611302 | 0.73 | MTNR1A (0.42) | — | |
| SCHEMBL7508213 | 0.73 | MTNR1A (0.42) | — | |
| SCHEMBL7121703 | 0.73 | MTNR1A (0.42) | — | |
| SCHEMBL7544832 | 0.73 | MTNR1A (0.50) | — | |
| SCHEMBL7118665 | 0.73 | CCNT1 (0.39) | CCNT1CDK9MMP2MMP3SYK | |
| SCHEMBL7118426 | 0.73 | CCNT1 (0.39) | CCNT1CDK9MMP2MMP3SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912561-A1 | 3-PHENYL-FURAN-(5H)-2-ONE AND DIHYDROFURAN-2-ONE DERIVATIVES AS ANTIBACTERIAL AGENTS | AstraZeneca AB (SE) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997043280-A1 | 3-PHENYL-FURAN-(5H)-2-ONE AND DIHYDROFURAN-2-ONE DERIVATIVES AS ANTIBACTERIAL AGENTS | ZENECA LIMITED (GB) | 1997-11-20 | — | — | WO | disclosed |