Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DUT | P33316 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19171550 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDLMNAALDH1A1POLB | |
| SCHEMBL10013998 | 0.80 | CACNA1H (0.46) | SMN1; SMN2HPGDLMNAALDH1A1POLB | |
| SCHEMBL2164003 | 0.79 | — | — | |
| SCHEMBL10083606 | 0.79 | — | — | |
| SCHEMBL16216124 | 0.79 | — | — | |
| SCHEMBL9116620 | 0.79 | ALDH1A1 (0.58) | SMN1; SMN2HPGDLMNAALDH1A1POLB | |
| SCHEMBL23772645 | 0.77 | ALDH1A1 (0.56) | SMN1; SMN2HPGDLMNAALDH1A1POLB | |
| SCHEMBL10170 | 0.77 | HDAC2 (0.52) | SMN1; SMN2HPGDALDH1A1POLBHDAC2 | |
| SCHEMBL3902710 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDLMNAALDH1A1POLB | |
| SCHEMBL23772642 | 0.77 | ALDH1A1 (0.56) | SMN1; SMN2HPGDLMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150598-B1 | SUBSTITUTED TROPANE DERIVATIVES | TOA EIYO LTD (JP) | 2019-02-13 | — | — | EP | disclosed |
| US-9856250-B2 | Substituted tropane derivatives | TOA EIYO LTD. (JP) | 2018-01-02 | — | — | US | disclosed |
| US-20170190699-A1 | SUBSTITUTED TROPANE DERIVATIVES | TOA EIYO LTD. (JP) | 2017-07-06 | — | — | US | disclosed |
| EP-3150598-A1 | SUBSTITUTED TROPANE DERIVATIVES | TOA Eiyo Ltd. (JP) | 2017-04-05 | — | — | EP | disclosed |
| US-8084395-B2 | 4-aza indole derivatives and their use as fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100184598-A1 | 4-AZA INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-07-22 | — | — | US | disclosed |
| EP-0395313-B1 | Tertiary alkyl functionalized piperazine derivatives | AMERICAN HOME PROD (US) | 1999-12-15 | — | — | EP | disclosed |
| EP-0955296-A2 | Tertiary alkyl functionalized piperazine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-10 | — | — | EP | disclosed |
| US-4988814-A | Antidepressants and/or anxiolytic agents | AMERICAN HOME PRODUCTS CORP. (US) | 1991-01-29 | — | — | US | disclosed |
| EP-0395313-A2 | Tertiary alkyl functionalized piperazine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184598-A1 | 4-AZA INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | IDO1, INMT, AZI2 | SMN1; SMN2 4466/4885HPGD 958/4885LMNA 4312/4885 |
| US-20170190699-A1 | SUBSTITUTED TROPANE DERIVATIVES | CACNA1G, CACNA1H, CACNA1I | SMN1; SMN2 539/4885HPGD 2573/4885LMNA 931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.