Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 6/20 | 0.58 |
| ▸ | GSK3A | P49840 | 2/20 | 0.53 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | PNP | P00491 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | KRAS | P01116 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450059 | 0.85 | HINT1 (0.73) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL20444711 | 0.85 | HINT1 (0.61) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL16359926 | 0.85 | HINT1 (0.61) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL1639395 | 0.85 | HINT1 (0.61) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL23425431 | 0.85 | HINT1 (0.61) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL23679991 | 0.85 | HINT1 (0.61) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL17972356 | 0.85 | HINT1 (0.61) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL17976623 | 0.85 | HINT1 (0.61) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL22883381 | 0.85 | HINT1 (0.61) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL1374872 | 0.85 | HINT1 (0.61) | HINT1GSK3ARPS6KA3MAPK14NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942916-A2 | NUCLEOSIDES | Medivir Aktiebolag (SE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998021223-A1 | NUCLEOSIDES | MEDIVIR AB (SE) | 1998-05-22 | — | — | WO | disclosed |