Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445555 | 1.00 | GAA (0.40) | GAAMAPK1RXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8822870 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HTTMRGPRX4MAPT | |
| SCHEMBL8822868 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HTTMRGPRX4MAPT | |
| SCHEMBL9394595 | 0.83 | — | — | |
| SCHEMBL8822721 | 0.82 | RAPGEF3 (0.34) | ALDH1A1SMN1; SMN2MRGPRX4MAPTTDP1 | |
| SCHEMBL8822723 | 0.82 | RAPGEF3 (0.34) | ALDH1A1SMN1; SMN2MRGPRX4MAPTTDP1 | |
| SCHEMBL8822748 | 0.75 | NPSR1 (0.46) | ALDH1A1CES2MAPTKDM4EHPGD | |
| SCHEMBL8822756 | 0.75 | NPSR1 (0.46) | ALDH1A1CES2MAPTKDM4EHPGD | |
| SCHEMBL5743661 | 0.73 | GAA (0.37) | GAAMAPK1RXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3326397 | 0.73 | GAA (0.37) | GAAMAPK1RXFP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460940-B1 | Pesticidal 1-arylpyrroles | RHONE POULENC AGROCHIMIE (FR) | 1999-01-27 | — | — | EP | disclosed |
| EP-0372982-B1 | Pyrrole insecticides | RHONE POULENC AGROCHIMIE (FR) | 1997-07-02 | — | — | EP | disclosed |
| US-5506260-A | INSECTICIDES, ACARICIDES, NEMATOCIDES | RHONE-POULENC AG COMPANY (US) | 1996-04-09 | — | — | US | disclosed |
| US-5187185-A | Pesticidal 1-arylpyrroles | RHONE-POULENC AG COMPANY (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0460940-A1 | Pesticidal 1-arylpyrroles | RHONE-POULENC AGROCHIMIE (FR) | 1991-12-11 | — | — | EP | disclosed |
| EP-0372982-A2 | Pyrrole insecticides | RHONE-POULENC AGROCHIMIE (FR) | 1990-06-13 | — | — | EP | disclosed |