Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | RAPGEF3 | O95398 | 7/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5743661 | 1.00 | GAA (0.37) | GAAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL6576619 | 0.86 | GAA (0.31) | GAAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL6576612 | 0.83 | KDM4E (0.31) | GAAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL2758643 | 0.83 | RAPGEF3 (0.32) | GAAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL6258551 | 0.78 | RAPGEF3 (0.38) | GAAALDH1A1SMN1; SMN2MAPTRAPGEF3 | |
| SCHEMBL9192973 | 0.78 | ABCB1 (0.45) | GAAALDH1A1KDM4EMAPTRAPGEF3 | |
| SCHEMBL8445555 | 0.73 | GAA (0.40) | GAAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL8445554 | 0.73 | GAA (0.40) | GAAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL7744125 | 0.73 | NPSR1 (0.43) | GAAALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL7744122 | 0.73 | NPSR1 (0.43) | GAAALDH1A1SMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258973-B1 | OXIDATION | RHONE-POULENC AGRO (FR) | 2001-07-10 | — | — | US | claimed |
| US-6084105-A | Processes for preparing pesticidal intermediates | RHONE-POULENC AGRO (FR) | 2000-07-04 | — | — | US | claimed |
| EP-2443093-B1 | PROCESS FOR THE PREPARATION OF PYRAZOLE DERIVATIVES | BASF SE (DE) | 2013-07-03 | — | — | EP | disclosed |
| US-8288563-B2 | Process for the preparation of pyrazole derivatives | BASF SE (DE) | 2012-10-16 | — | — | US | disclosed |
| US-20120004421-A1 | Process for the preparation of pyrazole derivatives | BASF SE (DE) | 2012-01-05 | — | — | US | disclosed |
| WO-2010105969-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE DERIVATIVES | BASF SE (DE) | 2010-09-23 | — | — | WO | disclosed |
| US-7094906-B2 | Processes for preparing pesticidal intermediates | Basf Agro B.V. Arnthem (NL) Wädenswil-Branch (CH) | 2006-08-22 | — | — | US | disclosed |
| EP-0952145-B1 | Process for preparing pesticidal intermediates | BASF AGRO BV (CH) | 2005-10-05 | — | — | EP | disclosed |
| EP-1073627-B1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | BAYER AGRICULTURE LTD (GB) | 2004-12-01 | — | — | EP | disclosed |
| US-20040198985-A1 | Processes for preparing pesticidal intermediates | AVENTIS AGRICULTURE LTD. (GB) | 2004-10-07 | — | — | US | disclosed |
| US-6673956-B2 | INTERMEDIATES (PARTICULARLY 2-(ARYLHYDRAZINO)SUCCINONITRILE COMPOUNDS AND 3-(ARYLHYDRAZONO)PROPIONITRILE DERIVATIVES FOR PESTICIDES, BY REACTING DIALKOXYPROPIONITRILE WITH AN ACID ADDITION SALT OF ARYLHYDRAZINE | AVENTIS AGRICULTURE LTD. (GB) | 2004-01-06 | — | — | US | disclosed |
| EP-0966445-B1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | AVENTIS CROPSCIENCE SA (FR) | 2001-07-25 | — | — | EP | disclosed |
| US-6258973-B1 | OXIDATION | RHONE-POULENC AGRO (FR) | 2001-07-10 | — | — | US | disclosed |
| EP-1073627-A1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | AVENTIS AGRICULTURE LTD. (GB) | 2001-02-07 | — | — | EP | disclosed |
| US-6084105-A | Processes for preparing pesticidal intermediates | RHONE-POULENC AGRO (FR) | 2000-07-04 | — | — | US | disclosed |
| EP-0966445-A1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | RHONE-POULENC AGRO (FR) | 1999-12-29 | — | — | EP | disclosed |
| WO-1999054288-A1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | AVENTIS AGRICULTURE LTD. (GB) | 1999-10-28 | — | — | WO | disclosed |
| EP-0952144-A1 | Processes for preparing pesticidal intermediates | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-10-27 | — | — | EP | disclosed |
| EP-0952145-A1 | Process for preparing pesticidal intermediates | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998039302-A1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | RHONE-POULENC AGRO (FR) | 1998-09-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198985-A1 | Processes for preparing pesticidal intermediates | SFXN3, SFXN1, CYP4F3 | GAA 4661/4885ALDH1A1 3068/4885SMN1; SMN2 3254/4885 |
| US-20120004421-A1 | Process for the preparation of pyrazole derivatives | CBR3, CBR1, C1S | GAA 4822/4885ALDH1A1 1827/4885SMN1; SMN2 4065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.