Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | WRN | Q14191 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3114270 | 0.90 | NAAA (0.56) | NAAAALDH1A1TSHRDGKAGAA | |
| SCHEMBL12673159 | 0.90 | NAAA (0.56) | NAAAALDH1A1TSHRDGKAGAA | |
| SCHEMBL347888 | 0.90 | NAAA (0.56) | NAAAALDH1A1TSHRDGKAGAA | |
| SCHEMBL181724 | 0.90 | NAAA (0.56) | NAAAALDH1A1TSHRDGKAGAA | |
| SCHEMBL50301 | 0.87 | NAAA (0.64) | NAAAALDH1A1TSHRDGKAGAA | |
| SCHEMBL31516165 | 0.86 | NAAA (0.43) | NAAAALDH1A1TSHRDGKAGAA | |
| SCHEMBL16616581 | 0.86 | NAAA (0.43) | NAAAALDH1A1TSHRDGKAGAA | |
| SCHEMBL448527 | 0.85 | NAAA (0.52) | NAAAALDH1A1TSHRDGKAGAA | |
| SCHEMBL106760 | 0.85 | ALDH1A1 (0.62) | NAAAALDH1A1TSHRDGKAGAA | |
| SCHEMBL11633352 | 0.84 | NAAA (0.48) | NAAAALDH1A1TSHRGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704445-B1 | Preparation of N-9 substituted guanine compounds | HOFFMANN LA ROCHE (CH) | 1999-04-21 | — | — | EP | disclosed |
| US-5565565-A | Preparation of N-9 substituted guanine compounds | SYNTEX (U.S.A.) INC. (US) | 1996-10-15 | — | — | US | disclosed |
| EP-0704445-A1 | Preparation of N-9 substituted guanine compounds | F. Hoffmann-La Roche AG (CH) | 1996-04-03 | — | — | EP | disclosed |