Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.59 |
| ▸ | MMP9 | P14780 | 6/20 | 0.52 |
| ▸ | MMP2 | P08253 | 8/20 | 0.51 |
| ▸ | MMP13 | P45452 | 8/20 | 0.51 |
| ▸ | MMP3 | P08254 | 5/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | MMP7 | P09237 | 2/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10021355 | 0.88 | MMP9 (0.70) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL10830548 | 0.85 | ADAMTS4 (0.66) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL7322447 | 0.85 | ADAMTS4 (0.66) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL14191405 | 0.84 | ADAMTS4 (0.55) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL8448397 | 0.82 | MMP9 (0.58) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL8450205 | 0.81 | MMP9 (0.75) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL8449004 | 0.81 | MMP9 (0.75) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL8448908 | 0.80 | ADAMTS4 (0.59) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL8446616 | 0.80 | ADAMTS4 (0.61) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL8446569 | 0.78 | ADAMTS4 (0.59) | ADAMTS4MMP9MMP2MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |