Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.58 |
| ▸ | MMP9 | P14780 | 5/20 | 0.55 |
| ▸ | MMP2 | P08253 | 7/20 | 0.52 |
| ▸ | MMP13 | P45452 | 5/20 | 0.52 |
| ▸ | MMP3 | P08254 | 3/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP7 | P09237 | 1/20 | 0.50 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | FPR1 | P21462 | 1/20 | 0.48 |
| ▸ | FPR3 | P25089 | 1/20 | 0.48 |
| ▸ | GPR183 | P32249 | 1/20 | 0.48 |
| ▸ | APLNR | P35414 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450205 | 0.84 | MMP9 (0.75) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL8449004 | 0.84 | MMP9 (0.75) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL8450122 | 0.84 | FFAR1 (0.49) | ADAMTS4FFAR1MMP9MMP2MMP13 | |
| SCHEMBL8448397 | 0.80 | MMP9 (0.58) | ADAMTS4FFAR1MMP9MMP2MMP13 | |
| SCHEMBL8445778 | 0.80 | ADAMTS4 (0.59) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL8446616 | 0.80 | ADAMTS4 (0.61) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL8446569 | 0.78 | ADAMTS4 (0.59) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL702794 | 0.78 | ADAMTS4 (0.81) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL790069 | 0.78 | ADAMTS4 (0.81) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL702793 | 0.78 | ADAMTS4 (0.81) | ADAMTS4MMP9MMP2MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |