Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNC1 | P63316 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | P4HB | P07237 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445774 | 0.81 | ATM (0.42) | NPC1MEN1KMT2AALDH1A1HDAC1 | |
| SCHEMBL8448260 | 0.75 | FFAR1 (0.45) | CA12CA1CA9CA2 | |
| SCHEMBL8445800 | 0.74 | CA12 (0.36) | CA12CA1CA9CA2 | |
| SCHEMBL8450007 | 0.74 | CA12 (0.36) | CA12CA1CA9CA2 | |
| SCHEMBL8446520 | 0.71 | CA12 (0.33) | CA12CA1CA9CA2 | |
| SCHEMBL8446610 | 0.70 | CA12 (0.48) | CA12CA1CA9CA2GAA | |
| SCHEMBL8450888 | 0.67 | POLB (0.35) | TNNC1LMNAP4HBPOLBMMP3 | |
| SCHEMBL8450891 | 0.67 | POLB (0.35) | TNNC1LMNAP4HBPOLBMMP3 | |
| SCHEMBL8446263 | 0.66 | ADAMTS4 (0.52) | MMP3ALDH1A1 | |
| SCHEMBL8446264 | 0.66 | ADAMTS4 (0.52) | MMP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |