Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 3/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP14 | P50281 | 2/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450891 | 1.00 | POLB (0.35) | POLBLMNAMMP3MAOAMAOB | |
| SCHEMBL8450038 | 0.76 | NPSR1 (0.36) | MMP3MMP13MMP1MMP2MMP9 | |
| SCHEMBL8446063 | 0.76 | HSD17B10 (0.44) | MMP13MMP1MMP2MMP9MMP14 | |
| SCHEMBL8446061 | 0.76 | HSD17B10 (0.44) | MMP13MMP1MMP2MMP9MMP14 | |
| SCHEMBL8446548 | 0.74 | HAO1 (0.35) | MMP3MAOAMAOBMMP13MMP1 | |
| SCHEMBL8445750 | 0.71 | MMP9 (0.42) | POLBMMP3MMP13MMP2MMP9 | |
| SCHEMBL8446563 | 0.70 | MMP13 (0.36) | MMP13 | |
| SCHEMBL8445793 | 0.67 | TNNC1 (0.34) | POLBLMNAMMP3P4HBTNNC1 | |
| SCHEMBL8446263 | 0.66 | ADAMTS4 (0.52) | MMP3MMP13MMP1MMP2MMP9 | |
| SCHEMBL8446264 | 0.66 | ADAMTS4 (0.52) | MMP3MMP13MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |