Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 10/20 | 0.59 |
| ▸ | MMP9 | P14780 | 8/20 | 0.59 |
| ▸ | MMP1 | P03956 | 8/20 | 0.59 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.59 |
| ▸ | MMP2 | P08253 | 6/20 | 0.50 |
| ▸ | MMP3 | P08254 | 5/20 | 0.46 |
| ▸ | MMP7 | P09237 | 4/20 | 0.46 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450013 | 1.00 | MMP13 (0.59) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL8448589 | 0.92 | MMP13 (0.56) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL8448264 | 0.91 | MMP13 (0.55) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL8446066 | 0.88 | MMP2 (0.59) | MMP13MMP9MMP1MMP2MMP3 | |
| SCHEMBL8446561 | 0.88 | MMP2 (0.59) | MMP13MMP9MMP1MMP2MMP3 | |
| SCHEMBL8446522 | 0.83 | MMP9 (0.65) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL8446571 | 0.82 | MMP9 (0.64) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL8446612 | 0.82 | MMP9 (0.64) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL8446074 | 0.81 | MMP2 (0.64) | MMP13MMP9MMP1MMP2MMP3 | |
| SCHEMBL8450866 | 0.81 | MMP2 (0.62) | MMP13MMP9MMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |