SCHEMBL8445998

SCHEMBL8445998

Cc1cn(CCCNC(C)(C)c2ccc(Cl)cc2)cn1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
QPCTL Q9NXS2 1/20 0.48
QPCT Q16769 19/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8444492 0.84 QPCTL (0.37) QPCTLQPCT
SCHEMBL7868474 0.82 CYP2C9 (0.40) QPCTL
SCHEMBL8446165 0.81 L3MBTL1 (0.49) QPCTL
Hydrochloric Acid SCHEMBL7873720 0.81 TDP1 (0.41) QPCTL
SCHEMBL7877119 0.79 SMN1; SMN2 (0.40) QPCTL
SCHEMBL8443962 0.78 LMNA (0.56) QPCT
Hydrochloric Acid SCHEMBL2887150 0.77 LMNA (0.55) QPCT
SCHEMBL8443123 0.77 NPSR1 (0.33) QPCTL
SCHEMBL8446891 0.77 QPCTL (0.41) QPCTLQPCT
SCHEMBL8445814 0.76 CHRM2 (0.50) QPCTLQPCT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5547972-A 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES THE BOOTS COMPANY PLC (GB) 1996-08-20 US claimed
EP-0618907-B1 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS BRITISH TECH GROUP INT (GB) 1999-04-28 EP disclosed
CN-1037511-C Therapeutic agents BOOTS CO PLC (GB) 1998-02-25 CN disclosed
US-5547972-A 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES THE BOOTS COMPANY PLC (GB) 1996-08-20 US disclosed
CN-1096781-A The therapeutical agent that contains 1-(aralkyl-aminoalkyl) imidazolium compounds BOOTS CO PLC (GB) 1994-12-28 CN disclosed
EP-0618907-A1 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS Knoll AG (DE) 1994-10-12 EP disclosed
WO-1993013075-A1 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS THE BOOTS COMPANY PLC (GB) 1993-07-08 WO disclosed