Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.35 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7873720 | 0.99 | TDP1 (0.41) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL8444492 | 0.86 | QPCTL (0.37) | CYP2C9CYP2C19CPB2QPCTLLMNA | |
| SCHEMBL9022145 | 0.82 | KDM4E (0.35) | CYP2C19TDP1CPB2LMNA | |
| SCHEMBL8445998 | 0.82 | QPCTL (0.48) | QPCTL | |
| SCHEMBL7877119 | 0.81 | SMN1; SMN2 (0.40) | CYP2C9CYP2C19TDP1CPB2QPCTL | |
| SCHEMBL7875247 | 0.81 | ESRRG (0.42) | — | |
| SCHEMBL7876986 | 0.80 | ALDH1A1 (0.41) | LMNA | |
| SCHEMBL8648870 | 0.76 | CYP2C9 (0.36) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL8446165 | 0.76 | L3MBTL1 (0.49) | TDP1QPCTLLMNA | |
| Hydrochloric Acid SCHEMBL8648938 | 0.76 | TDP1 (0.37) | CYP2C9TSHRCYP2C19MTORHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| US-5780642-A | NON-STEROIDAL ANTIINFLAMMATORY AGENT WHICH BLOCKS RELEASE OF ARACHIDONIC ACID FROM PHOSPHOLIPIDS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |