Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444566 | 0.77 | CYP19A1 (0.44) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL8447183 | 0.77 | CYP2A6 (0.51) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL10955545 | 0.77 | OGG1 (0.53) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL11286288 | 0.76 | CYP11B1 (0.61) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL6571544 | 0.74 | CYP1A2 (0.61) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL8447144 | 0.73 | CYP2A6 (0.56) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| Hydrochloric Acid SCHEMBL8446022 | 0.72 | CYP1A2 (0.55) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL11639842 | 0.72 | CYP19A1 (0.55) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL11274893 | 0.72 | CYP2A6 (0.55) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL570342 | 0.71 | CYP11B1 (1.00) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | disclosed |
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |