Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | WDR5 | P61964 | 2/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444499 | 0.78 | LMNA (0.47) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL8446102 | 0.77 | CYP19A1 (0.54) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL8949197 | 0.75 | MEN1 (0.58) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23747316 | 0.75 | NAMPT (0.67) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL11286288 | 0.74 | CYP11B1 (0.61) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL1709264 | 0.73 | MEN1 (0.63) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11639842 | 0.73 | CYP19A1 (0.55) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL20602561 | 0.73 | CYP11B1 (0.61) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL5076692 | 0.72 | PKM (0.57) | CYP19A1LMNACYP3A4TBXAS1 | |
| SCHEMBL10759280 | 0.72 | ALDH1A1 (0.62) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | disclosed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |