Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 5/20 | 0.35 |
| ▸ | ITPR2 | Q14571 | 2/20 | 0.35 |
| ▸ | ITPR1 | Q14643 | 2/20 | 0.35 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.35 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | LY96 | Q9Y6Y9 | 6/20 | 0.35 |
| ▸ | TLR4 | O00206 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3075859 | 0.92 | ALDH1A1 (0.38) | LY96TLR4ALDH1A1LMNA | |
| SCHEMBL9000958 | 0.85 | ITPR3 (0.52) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL3080244 | 0.83 | LY96 (0.43) | LY96TLR4 | |
| SCHEMBL3080744 | 0.81 | LY96 (0.47) | LY96TLR4 | |
| SCHEMBL8498938 | 0.81 | ITPR3 (0.55) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL9393011 | 0.79 | ITPR3 (0.52) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL3087052 | 0.78 | PPARD (0.34) | LY96TLR4 | |
| SCHEMBL14094698 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNA | |
| SCHEMBL8444060 | 0.77 | GPR55 (0.37) | AKT1LY96TLR4SMPD1 | |
| SCHEMBL5667749 | 0.76 | ITPR3 (0.43) | ITPR3ITPR2ITPR1INPP5AINPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910383-A1 | THE USE OF GROWTH FACTOR MODULATING COMPOUNDS | PERSTORP AB (SE) | 1999-04-28 | — | — | EP | disclosed |
| WO-1997049408-A1 | THE USE OF GROWTH FACTOR MODULATING COMPOUNDS | PERSTORP AB (SE) | 1997-12-31 | — | — | WO | disclosed |