Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446884 | 1.00 | PTGS2 (0.36) | PTGS2HIF1ALMNAPOLBALDH1A1 | |
| SCHEMBL8446178 | 0.82 | PTGS2 (0.39) | PTGS2HIF1ALMNAPOLBALDH1A1 | |
| SCHEMBL8446121 | 0.79 | PTGS2 (0.37) | PTGS2HIF1ALMNAPOLBALDH1A1 | |
| SCHEMBL8446120 | 0.79 | PTGS2 (0.37) | PTGS2HIF1ALMNAPOLBALDH1A1 | |
| SCHEMBL8447507 | 0.78 | HIF1A (0.46) | PTGS2HIF1ALMNAALDH1A1HTT | |
| SCHEMBL8444517 | 0.78 | HIF1A (0.60) | PTGS2HIF1ALMNAALDH1A1HTT | |
| SCHEMBL8447501 | 0.78 | HIF1A (0.46) | PTGS2HIF1ALMNAALDH1A1HTT | |
| SCHEMBL8444521 | 0.78 | HIF1A (0.60) | PTGS2HIF1ALMNAALDH1A1HTT | |
| SCHEMBL6693332 | 0.77 | PTGS2 (0.39) | PTGS2HIF1ALMNAALDH1A1HTT | |
| SCHEMBL13148667 | 0.76 | HIF1A (0.46) | PTGS2HIF1ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893433-A1 | ALPHA-ALKOXYIMINOBENZYL DERIVATIVES AND AGRICULTURAL CHEMICALS CONTAINING THEM AS ACTIVE INGREDIENTS | SHIONOGI & CO., LTD. (JP) | 1999-01-27 | — | — | EP | disclosed |