Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.40 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8070501 | 0.99 | SLC9A1 (0.39) | SLC9A1SLC9A2KDM4EMAPT | |
| SCHEMBL8070556 | 0.89 | MAPT (0.47) | KDM4EMAPT | |
| SCHEMBL8446233 | 0.87 | MAPT (0.36) | KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL8068552 | 0.86 | MAPT (0.35) | KDM4EMAPT | |
| SCHEMBL8444778 | 0.80 | SLC9A1 (0.50) | SLC9A1 | |
| Hydrochloric Acid SCHEMBL8068489 | 0.79 | SLC9A1 (0.49) | SLC9A1 | |
| Hydrochloric Acid SCHEMBL8077076 | 0.78 | KMT2A (0.52) | SLC9A1 | |
| SCHEMBL8446349 | 0.76 | SLC9A1 (0.53) | SLC9A1SLC9A2 | |
| Hydrochloric Acid SCHEMBL8059477 | 0.75 | SLC9A1 (0.52) | SLC9A1SLC9A2 | |
| SCHEMBL8070495 | 0.74 | KDM4E (0.67) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723956-B1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AG (DE) | 1999-10-13 | — | — | EP | claimed |