Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8445991 | 0.87 | KDM4E (0.51) | KDM4EMAPTRAB9AHTTLMNA | |
| SCHEMBL8070556 | 0.85 | MAPT (0.47) | KDM4EMAPTHTTTSHRPKM | |
| SCHEMBL8059524 | 0.81 | KDM4E (0.50) | KDM4EMAPTHTTLMNAGAA | |
| SCHEMBL29123954 | 0.81 | MAPT (1.00) | KDM4EMAPTRAB9AHTTGAA | |
| SCHEMBL8446010 | 0.79 | MAPT (0.42) | KDM4EMAPTHTTLMNASMN1; SMN2 | |
| SCHEMBL8068849 | 0.78 | ALDH1A1 (0.54) | KDM4EMAPTLMNATSHRSMN1; SMN2 | |
| SCHEMBL29451605 | 0.77 | KDM4E (0.75) | KDM4EMAPTRAB9A | |
| SCHEMBL8068480 | 0.76 | CYP19A1 (0.55) | POLBALDH1A1 | |
| SCHEMBL8068934 | 0.76 | SIGMAR1 (0.51) | KDM4EMAPTLMNAGAASMN1; SMN2 | |
| SCHEMBL8446994 | 0.76 | RAB9A (0.53) | KDM4EMAPTRAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |