Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 4/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8068552 | 0.99 | MAPT (0.35) | MAPTKDM4EMRGPRX1F2PLG | |
| SCHEMBL8070556 | 0.88 | MAPT (0.47) | MAPTKDM4EHTTTSHR | |
| SCHEMBL8446235 | 0.87 | SLC9A1 (0.40) | MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL8070501 | 0.86 | SLC9A1 (0.39) | MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL8445991 | 0.86 | KDM4E (0.51) | MAPTKDM4EF2F10PRSS1 | |
| SCHEMBL8446232 | 0.82 | MRGPRX1 (0.35) | MRGPRX1F10ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8068549 | 0.81 | MRGPRX1 (0.34) | MRGPRX1F10ALDH1A1LMNA | |
| SCHEMBL8444243 | 0.80 | ALDH1A1 (0.53) | ALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL8444776 | 0.80 | SIGMAR1 (0.46) | ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8070683 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723956-B1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AG (DE) | 1999-10-13 | — | — | EP | claimed |