Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 14/20 | 0.67 |
| ▸ | MMP2 | P08253 | 13/20 | 0.67 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.60 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.58 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8451018 | 0.92 | KCNA5 (0.61) | MMP9MMP2ADAM17KCNA5 | |
| SCHEMBL8446620 | 0.86 | MMP9 (0.74) | MMP9MMP2ADAM17KCNA5 | |
| SCHEMBL8445641 | 0.82 | MMP9 (0.77) | MMP9MMP2ADAM17KCNA5 | |
| SCHEMBL8448379 | 0.81 | MMP9 (0.66) | MMP9MMP2ADAM17KCNA5 | |
| SCHEMBL8446523 | 0.80 | MMP9 (0.92) | MMP9MMP2ADAM17KCNA5 | |
| SCHEMBL8445610 | 0.79 | MMP2 (0.52) | MMP9MMP2ADAM17MMP3 | |
| SCHEMBL8446559 | 0.78 | MMP9 (1.00) | MMP9MMP2ADAM17KCNA5 | |
| SCHEMBL8446521 | 0.78 | MMP9 (1.00) | MMP9MMP2ADAM17KCNA5 | |
| SCHEMBL8450882 | 0.78 | KCNA5 (0.62) | MMP9MMP2ADAM17KCNA5 | |
| SCHEMBL8668400 | 0.78 | KCNA5 (0.67) | MMP9MMP2ADAM17KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |