Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 16/20 | 1.00 |
| ▸ | MMP2 | P08253 | 14/20 | 1.00 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.69 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.68 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446521 | 1.00 | MMP9 (1.00) | MMP9MMP2KCNA5ADAM17NR3C1 | |
| SCHEMBL3154749 | 0.94 | MMP9 (0.88) | MMP9MMP2KCNA5ADAM17NR3C1 | |
| SCHEMBL3154764 | 0.94 | MMP9 (0.88) | MMP9MMP2KCNA5ADAM17NR3C1 | |
| SCHEMBL12247616 | 0.93 | MMP9 (0.88) | MMP9MMP2KCNA5ADAM17 | |
| SCHEMBL8446523 | 0.92 | MMP9 (0.92) | MMP9MMP2KCNA5ADAM17NR3C1 | |
| SCHEMBL8449351 | 0.90 | MMP9 (0.82) | MMP9MMP2KCNA5ADAM17NR3C1 | |
| SCHEMBL8448255 | 0.90 | MMP9 (0.82) | MMP9MMP2KCNA5ADAM17NR3C1 | |
| SCHEMBL8448733 | 0.90 | MMP9 (0.82) | MMP9MMP2KCNA5ADAM17NR3C1 | |
| SCHEMBL12247609 | 0.90 | MMP9 (1.00) | MMP9MMP2KCNA5ADAM17 | |
| SCHEMBL2381488 | 0.90 | MMP9 (1.00) | MMP9MMP2KCNA5ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |