SCHEMBL8446281

Cc1ccc(C#Cc2ccc(S(=O)(=O)N[C@@H](C(=O)O)C(C)C)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	MMP9	P14780	12/20	1.00

▸	MMP2	P08253	15/20	0.77

▸	MMP3	P08254	11/20	0.77

▸	MMP13	P45452	11/20	0.77

▸	MMP1	P03956	9/20	0.77

▸	MMP7	P09237	9/20	0.77

▸	ADAMTS4	O75173	2/20	0.62

▸	SLC1A3	P43003	1/20	0.62

▸	SLC1A2	P43004	1/20	0.62

▸	SLC1A1	P43005	1/20	0.62

▸	MMP14	P50281	1/20	0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3964630	0.91	MMP9 (0.91)	MMP9MMP2MMP3MMP13MMP1
SCHEMBL6446613	0.91	MMP9 (0.91)	MMP9MMP2MMP3MMP13MMP1
SCHEMBL4588942	0.91	MMP9 (0.91)	MMP9MMP2MMP3MMP13MMP1
SCHEMBL7870619	0.87	MMP2 (1.00)	MMP9MMP2MMP3MMP13MMP1
SCHEMBL7870625	0.87	MMP2 (1.00)	MMP9MMP2MMP3MMP13MMP1
SCHEMBL8450205	0.86	MMP9 (0.75)	MMP9MMP2MMP3MMP13MMP1
SCHEMBL8449004	0.86	MMP9 (0.75)	MMP9MMP2MMP3MMP13MMP1
SCHEMBL6800772	0.83	MMP2 (0.77)	MMP9MMP2MMP3MMP13MMP1
SCHEMBL8446644	0.82	MMP9 (0.70)	MMP9MMP2MMP3MMP13MMP1
SCHEMBL10021355	0.82	MMP9 (0.70)	MMP9MMP2MMP3MMP13MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0915086-A1	PHENYLSULFONAMIDE DERIVATIVES	ONO PHARMACEUTICAL CO., LTD. (JP)	1999-05-12	—	—	EP	claimed
EP-0915086-A1	PHENYLSULFONAMIDE DERIVATIVES	ONO PHARMACEUTICAL CO., LTD. (JP)	1999-05-12	—	—	EP	disclosed