Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 9/20 | 0.70 |
| ▸ | MMP2 | P08253 | 9/20 | 0.53 |
| ▸ | MMP3 | P08254 | 6/20 | 0.53 |
| ▸ | MMP13 | P45452 | 6/20 | 0.53 |
| ▸ | MMP1 | P03956 | 5/20 | 0.53 |
| ▸ | MMP7 | P09237 | 5/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | HPN | P05981 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450035 | 0.88 | MMP9 (0.58) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL8449978 | 0.88 | MMP9 (0.58) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL10211049 | 0.85 | MMP13 (0.64) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL10208391 | 0.85 | MMP13 (0.64) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL1656271 | 0.82 | MMP9 (0.49) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL1659451 | 0.82 | MMP2 (0.54) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL8446281 | 0.82 | MMP9 (1.00) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL7667739 | 0.82 | MMP9 (0.59) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL7671437 | 0.82 | MMP9 (0.59) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL14176097 | 0.81 | MMP9 (0.47) | MMP9MMP2MMP3MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |