Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.51 |
| ▸ | GCGR | P47871 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALPL | P05186 | 2/20 | 0.47 |
| ▸ | ALPG | P10696 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8444771 | 0.99 | CA1 (0.51) | CA1CA2CA7CA13GCGR | |
| Hydrochloric Acid SCHEMBL8070136 | 0.87 | MAPT (0.40) | CA1CA2CA7CA13GCGR | |
| SCHEMBL8446364 | 0.87 | CA1 (0.55) | CA1CA2CA7CA13GCGR | |
| SCHEMBL8446986 | 0.84 | CTSZ (0.40) | CA1CA2CA7CA13MAPT | |
| Hydrochloric Acid SCHEMBL8521359 | 0.83 | CTSZ (0.40) | CA1CA2CA7CA13MAPT | |
| SCHEMBL8446360 | 0.83 | TSHR (0.45) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL8068543 | 0.82 | TSHR (0.45) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL8446098 | 0.81 | RAB9A (0.45) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8444221 | 0.78 | CYP3A4 (0.44) | MAPTALDH1A1SMN1; SMN2GAAHTT | |
| SCHEMBL8499411 | 0.77 | GCK (0.42) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723956-B1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AG (DE) | 1999-10-13 | — | — | EP | claimed |