Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA6 | P23280 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8521359 | 0.99 | CTSZ (0.40) | CTSZTSHRKDM4EHDAC1MAPT | |
| SCHEMBL8073894 | 0.86 | CTSZ (0.45) | CTSZTSHRKDM4EMAPTPOLB | |
| SCHEMBL8446988 | 0.85 | CTSZ (0.41) | CTSZ | |
| Hydrochloric Acid SCHEMBL8059598 | 0.84 | CTSZ (0.41) | CTSZ | |
| SCHEMBL8446359 | 0.84 | CA1 (0.51) | HDAC1MAPTPOLBATMALDH1A1 | |
| Hydrochloric Acid SCHEMBL8446098 | 0.83 | RAB9A (0.45) | KDM4EMAPTPOLBALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8444771 | 0.83 | CA1 (0.51) | HDAC1MAPTPOLBATMALDH1A1 | |
| Hydrochloric Acid SCHEMBL8444221 | 0.82 | CYP3A4 (0.44) | MAPTALDH1A1SMN1; SMN2THRATHRB | |
| SCHEMBL8446987 | 0.81 | GAA (0.39) | KDM4EMAPTALDH1A1SMN1; SMN2THRA | |
| Hydrochloric Acid SCHEMBL8059595 | 0.81 | GAA (0.38) | KDM4EMAPTALDH1A1SMN1; SMN2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723956-B1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AG (DE) | 1999-10-13 | — | — | EP | claimed |
| EP-0723956-A1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-31 | — | — | EP | disclosed |