SCHEMBL8446361

SCHEMBL8446361

CS(=O)(=O)c1cc(C(=O)N=C(N)N)ccc1Oc1ccc(C(=O)CSn2cnc3ccccc32)cc1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 2/20 0.40
SLC9A2 Q9UBY0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8072548 0.99 SLC9A1 (0.39) SLC9A1SLC9A2
SCHEMBL8073710 0.88 SMN1; SMN2 (0.38)
SCHEMBL8363877 0.76 SLC9A1 (0.56) SLC9A1SLC9A2
Hydrochloric Acid SCHEMBL8743851 0.75 SLC9A1 (0.55) SLC9A1SLC9A2
SCHEMBL8446988 0.75 CTSZ (0.41) SLC9A1SLC9A2
Hydrochloric Acid SCHEMBL8059598 0.74 CTSZ (0.41) SLC9A1SLC9A2
Hydrochloric Acid SCHEMBL8815133 0.74 PARP10 (0.47) SLC9A1SLC9A2
SCHEMBL8379275 0.73 SLC9A1 (0.55) SLC9A1SLC9A2
SCHEMBL8743807 0.73 SLC9A1 (0.55) SLC9A1SLC9A2
Hydrochloric Acid SCHEMBL8073898 0.73 CA12 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0723956-B1 Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them HOECHST AG (DE) 1999-10-13 EP claimed