Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446361 | 0.88 | SLC9A1 (0.40) | — | |
| Hydrochloric Acid SCHEMBL8072548 | 0.88 | SLC9A1 (0.39) | — | |
| SCHEMBL8446994 | 0.77 | RAB9A (0.53) | SMN1; SMN2LMNAMAPTTTRHPGD | |
| SCHEMBL8446364 | 0.75 | CA1 (0.55) | SMN1; SMN2HTTMAPTCA1CA2 | |
| SCHEMBL7995261 | 0.74 | TTR (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8073502 | 0.73 | TTR (0.51) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL8068490 | 0.73 | TTR (0.44) | SMN1; SMN2MAPTCA12CA1CA2 | |
| SCHEMBL8073894 | 0.72 | CTSZ (0.45) | TSHRHTTMAPTCA12CA1 | |
| SCHEMBL8815218 | 0.72 | NR4A2 (0.58) | SMN1; SMN2KMT2A | |
| SCHEMBL8059431 | 0.71 | CYP19A1 (0.51) | LMNACA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |