Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 12/20 | 0.82 |
| ▸ | MMP2 | P08253 | 11/20 | 0.82 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.62 |
| ▸ | MMP1 | P03956 | 1/20 | 0.61 |
| ▸ | MMP3 | P08254 | 1/20 | 0.61 |
| ▸ | MMP8 | P22894 | 1/20 | 0.61 |
| ▸ | MMP14 | P50281 | 1/20 | 0.61 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.61 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.61 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.57 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446521 | 0.90 | MMP9 (1.00) | MMP9MMP2NR3C1KCNA5ADAM17 | |
| SCHEMBL8446559 | 0.90 | MMP9 (1.00) | MMP9MMP2NR3C1KCNA5ADAM17 | |
| SCHEMBL8449351 | 0.89 | MMP9 (0.82) | MMP9MMP2NR3C1KCNA5ADAM17 | |
| SCHEMBL8448255 | 0.89 | MMP9 (0.82) | MMP9MMP2NR3C1KCNA5ADAM17 | |
| SCHEMBL7378965 | 0.86 | MMP9 (0.89) | MMP9MMP2NR3C1KCNA5HDAC2 | |
| SCHEMBL7378962 | 0.86 | MMP9 (0.89) | MMP9MMP2NR3C1KCNA5HDAC2 | |
| SCHEMBL7379195 | 0.85 | MMP9 (0.84) | MMP9MMP2NR3C1KCNA5HDAC2 | |
| SCHEMBL7379197 | 0.85 | MMP9 (0.84) | MMP9MMP2NR3C1KCNA5HDAC2 | |
| SCHEMBL22500545 | 0.84 | NR3C1 (0.70) | MMP9MMP2NR3C1MMP1MMP14 | |
| SCHEMBL22501220 | 0.84 | NR3C1 (0.70) | MMP9MMP2NR3C1MMP1MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |