Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 13/20 | 0.58 |
| ▸ | MMP2 | P08253 | 12/20 | 0.58 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450872 | 0.93 | MMP9 (0.60) | MMP9MMP2KCNA5KCNH2ADAM17 | |
| SCHEMBL8448675 | 0.92 | MMP9 (0.70) | MMP9MMP2KCNA5ADAM17 | |
| SCHEMBL8448551 | 0.89 | KCNA5 (0.58) | MMP9MMP2KCNA5KCNH2MMP8 | |
| SCHEMBL8446618 | 0.84 | MMP9 (0.72) | MMP9MMP2KCNA5ADAM17 | |
| SCHEMBL8448286 | 0.84 | MMP9 (0.66) | MMP9MMP2KCNA5KCNH2ADAM17 | |
| SCHEMBL8448720 | 0.83 | MMP9 (0.65) | MMP9MMP2KCNA5KCNH2MMP1 | |
| SCHEMBL8450863 | 0.83 | KCNA5 (0.73) | MMP9MMP2KCNA5KCNH2ADAM17 | |
| SCHEMBL8448503 | 0.82 | MMP9 (0.75) | MMP9MMP2KCNA5KCNH2ADAM17 | |
| SCHEMBL8448255 | 0.82 | MMP9 (0.82) | MMP9MMP2KCNA5KCNH2ADAM17 | |
| SCHEMBL8449351 | 0.82 | MMP9 (0.82) | MMP9MMP2KCNA5KCNH2ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |