Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446610 | 1.00 | CA12 (0.48) | CA12CA2CA9CA1MMP9 | |
| SCHEMBL8446520 | 0.88 | CA12 (0.33) | CA12CA2CA9CA1MMP9 | |
| SCHEMBL8445774 | 0.86 | ATM (0.42) | ALDH1A1AGERATMKEAP1NFE2L2 | |
| SCHEMBL8450007 | 0.83 | CA12 (0.36) | CA12CA2CA9CA1MMP9 | |
| SCHEMBL8445800 | 0.83 | CA12 (0.36) | CA12CA2CA9CA1MMP9 | |
| SCHEMBL8446537 | 0.82 | CA12 (0.44) | CA12CA2CA9CA1 | |
| SCHEMBL8448587 | 0.80 | FFAR1 (0.43) | CA12CA2CA9CA1MMP2 | |
| SCHEMBL8448260 | 0.79 | FFAR1 (0.45) | CA12CA2CA9CA1MMP2 | |
| SCHEMBL8446283 | 0.74 | MMP9 (0.47) | CA12CA2CA9CA1MMP9 | |
| SCHEMBL4916977 | 0.71 | ALDH1A1 (0.41) | CA12CA2CA9CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |