Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 8/20 | 0.47 |
| ▸ | MMP2 | P08253 | 5/20 | 0.47 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 5/20 | 0.43 |
| ▸ | MMP1 | P03956 | 4/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448391 | 0.89 | MMP9 (0.49) | MMP9MMP2MMP13MMP1ADAM17 | |
| SCHEMBL8445810 | 0.86 | MMP9 (0.46) | MMP9MMP2MMP13MMP1ADAM17 | |
| SCHEMBL8446284 | 0.85 | MMP9 (0.59) | MMP9MMP2AGERMMP13MMP1 | |
| SCHEMBL8448311 | 0.83 | MMP9 (0.45) | MMP9MMP2MMP13MMP1ADAM17 | |
| SCHEMBL8448761 | 0.82 | MMP9 (0.46) | MMP9MMP2MMP13MMP1CA12 | |
| SCHEMBL8451686 | 0.82 | MMP9 (0.45) | MMP9MMP2MMP13MMP1ADAM17 | |
| SCHEMBL8446650 | 0.81 | CA12 (0.38) | MMP9MMP2AGERMMP13MMP1 | |
| SCHEMBL8445864 | 0.81 | MMP9 (0.44) | MMP9MMP2MMP13MMP1CA12 | |
| SCHEMBL8446566 | 0.80 | MMP2 (0.51) | MMP9MMP2MMP13MMP8MMP3 | |
| SCHEMBL8450948 | 0.80 | HTT (0.39) | MMP9MMP13MMP1ADAM17CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |