Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 5/20 | 0.64 |
| ▸ | MMP2 | P08253 | 6/20 | 0.53 |
| ▸ | MMP3 | P08254 | 3/20 | 0.53 |
| ▸ | MMP13 | P45452 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138463 | 0.91 | TSHR (0.58) | MMP9MMP2MMP3MMP13TSHR | |
| SCHEMBL7889040 | 0.91 | TSHR (0.58) | MMP9MMP2MMP3MMP13TSHR | |
| SCHEMBL25269775 | 0.91 | TSHR (0.58) | MMP9MMP2MMP3MMP13TSHR | |
| SCHEMBL8445733 | 0.87 | MMP9 (0.49) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL8450035 | 0.87 | MMP9 (0.58) | MMP9MMP2MMP3MMP13TSHR | |
| SCHEMBL8449978 | 0.87 | MMP9 (0.58) | MMP9MMP2MMP3MMP13TSHR | |
| SCHEMBL8449004 | 0.86 | MMP9 (0.75) | MMP9MMP2MMP3MMP13TSHR | |
| SCHEMBL8450205 | 0.86 | MMP9 (0.75) | MMP9MMP2MMP3MMP13TSHR | |
| SCHEMBL8446571 | 0.83 | MMP9 (0.64) | MMP9MMP2MMP3MMP13TSHR | |
| SCHEMBL8446612 | 0.83 | MMP9 (0.64) | MMP9MMP2MMP3MMP13TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |