Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 10/20 | 0.49 |
| ▸ | MMP13 | P45452 | 9/20 | 0.49 |
| ▸ | MMP1 | P03956 | 7/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 8/20 | 0.44 |
| ▸ | MMP3 | P08254 | 4/20 | 0.43 |
| ▸ | MMP7 | P09237 | 4/20 | 0.43 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446641 | 0.87 | MMP9 (0.64) | MMP9MMP13MMP1CA14MMP2 | |
| SCHEMBL8446616 | 0.85 | ADAMTS4 (0.61) | MMP9MMP13MMP1ADAM17ADAMTS4 | |
| SCHEMBL8446522 | 0.83 | MMP9 (0.65) | MMP9MMP13MMP1ADAM17ADAMTS4 | |
| SCHEMBL25269775 | 0.80 | TSHR (0.58) | MMP9MMP13MMP1CA14ADAMTS4 | |
| SCHEMBL7889040 | 0.80 | TSHR (0.58) | MMP9MMP13MMP1CA14ADAMTS4 | |
| SCHEMBL7138463 | 0.80 | TSHR (0.58) | MMP9MMP13MMP1CA14ADAMTS4 | |
| SCHEMBL6506135 | 0.80 | ADAM17 (0.76) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL6329696 | 0.79 | HSD17B10 (0.60) | MMP9MMP13MMP1CA14MMP2 | |
| SCHEMBL29541363 | 0.79 | HSD17B10 (0.60) | MMP9MMP13MMP1CA14MMP2 | |
| SCHEMBL6329698 | 0.79 | HSD17B10 (0.60) | MMP9MMP13MMP1CA14MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |