SCHEMBL8447105

SCHEMBL8447105

O=[PH](O)OCCCCCCCCCCCCSC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 20/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1995372 0.78 KIF11 (0.56) KIF11
SCHEMBL8447103 0.77 KIF11 (0.44) KIF11
SCHEMBL9972416 0.76 KIF11 (0.46) KIF11
SCHEMBL12221713 0.76 CYP2C19 (0.47) —
SCHEMBL4534194 0.75 KIF11 (0.45) KIF11
SCHEMBL9889271 0.75 KIF11 (0.45) KIF11
SCHEMBL16653157 0.74 KIF11 (0.52) KIF11
SCHEMBL1345862 0.74 KIF11 (0.43) KIF11
SCHEMBL28634657 0.74 KIF11 (0.55) KIF11
SCHEMBL34052 0.74 KIF11 (0.55) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0637309-B1 METAL COATINGS BIOCOMPATIBLES LTD (GB) 1999-03-31 — — EP disclosed
US-5556710-A METAL COATINGS TO RENDER SURFACES BIOCOMPATIBLE BIOCOMPATIBLES LIMITED (GB) 1996-09-17 — — US disclosed
EP-0637309-A1 METAL COATINGS BIOCOMPATIBLES LIMITED (GB) 1995-02-08 — — EP disclosed
WO-1993022320-A1 METAL COATINGS BIOCOMPATIBLES LIMITED (GB) 1993-11-11 — — WO disclosed
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