Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 18/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4534194 | 1.00 | KIF11 (0.45) | KIF11MEN1THRBHTTKMT2A | |
| SCHEMBL4804833 | 0.87 | KIF11 (0.50) | KIF11 | |
| SCHEMBL4530986 | 0.87 | KIF11 (0.50) | KIF11 | |
| SCHEMBL4531442 | 0.85 | KIF11 (0.52) | KIF11 | |
| SCHEMBL1345862 | 0.84 | KIF11 (0.43) | KIF11 | |
| SCHEMBL8447104 | 0.82 | KIF11 (0.55) | KIF11 | |
| SCHEMBL34052 | 0.82 | KIF11 (0.55) | KIF11 | |
| SCHEMBL28634657 | 0.82 | KIF11 (0.55) | KIF11 | |
| SCHEMBL357884 | 0.79 | KIF11 (0.45) | KIF11 | |
| SCHEMBL1995372 | 0.79 | KIF11 (0.56) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150369816-A1 | Polypeptide Immobilization | UNIV CHICAGO (US) | 2015-12-24 | — | — | US | disclosed |
| US-9074300-B2 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO (US) | 2015-07-07 | — | — | US | disclosed |
| US-20120142547-A1 | POLYPEPTIDE IMMOBILIZATION | THE UNIVERSITY OF CHICAGO | 2012-06-07 | — | — | US | disclosed |
| US-7888055-B2 | Selectively binds with absolute control over orientation and density without requiring prior synthetic modification or purification to make a stable protein chip; rapid and irreversible; assaying kinase or protease activity | THE UNIVERSITY OF CHICAGO (US) | 2011-02-15 | — | — | US | disclosed |
| US-20080064606-A1 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064606-A1 | Polypeptide immobilization | QPCTL, SURF4, QPCT | KIF11 2785/4885MEN1 4440/4885THRB 353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.