SCHEMBL1345862

SCHEMBL1345862

O=C(O)COCCOCCOCCOCCOCCCCCCCCCCCSC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 18/20 0.43
SLC6A1 P30531 1/20 0.38
SLC6A11 P48066 1/20 0.38
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12308047 0.94 KIF11 (0.44) KIF11SLC6A1SLC6A11
SCHEMBL20750909 0.88 KIF11 (0.46) KIF11
SCHEMBL1347022 0.85 SMN1; SMN2 (0.40) KIF11
SCHEMBL9889271 0.84 KIF11 (0.45) KIF11
SCHEMBL4534194 0.84 KIF11 (0.45) KIF11
SCHEMBL6907826 0.79 HPGD (0.41) KIF11
SCHEMBL357884 0.78 KIF11 (0.45) KIF11
SCHEMBL18095510 0.78 KIF11 (0.45) KIF11SLC6A1HDAC1HDAC2
SCHEMBL3792783 0.77 KIF11 (0.50) KIF11HDAC1HDAC2
SCHEMBL34262 0.77 KIF11 (0.50) KIF11HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8062890-B2 Defined surfaces of self-assembled monolayers and stem cells WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2011-11-22 US disclosed
US-8062890-B2 Defined surfaces of self-assembled monolayers and stem cells WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2011-11-22 US disclosed
US-20070207543-A1 Defined surfaces of self-assembled monolayers and stem cells WISCONSIN ALUMNI RESEARCH FOUNDATION 2007-09-06 US disclosed