Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.52 |
| ▸ | ACE | P12821 | 8/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | CPA2 | P48052 | 1/20 | 0.42 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566002 | 0.93 | MME (0.61) | MMEACETACR1CTSLCTSB | |
| SCHEMBL7565990 | 0.93 | MME (0.61) | MMEACETACR1CTSLCTSB | |
| SCHEMBL8453133 | 0.91 | MME (0.49) | MMEACETACR1CTSLCTSB | |
| SCHEMBL8446481 | 0.88 | MME (0.62) | MMEACETACR1CTSLCTSB | |
| SCHEMBL8450819 | 0.86 | MME (0.50) | MMEACETACR1CTSBCPA1 | |
| SCHEMBL8447138 | 0.86 | MME (0.58) | MMEACETACR1CTSLCTSB | |
| SCHEMBL8446463 | 0.86 | MME (0.55) | MMEACETACR1CTSLCTSB | |
| SCHEMBL8450109 | 0.86 | MME (0.52) | MMEACETACR1CTSLCTSB | |
| SCHEMBL8446428 | 0.85 | MME (0.52) | MMEACETACR1CTSB | |
| SCHEMBL8033713 | 0.85 | MME (0.73) | MMEACETACR1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |