Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.42 |
| ▸ | ACE | P12821 | 4/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | CPA2 | P48052 | 2/20 | 0.39 |
| ▸ | CPA4 | Q9UI42 | 2/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453137 | 0.91 | MME (0.43) | MMEACECPA1CPA2CPA4 | |
| SCHEMBL8446482 | 0.87 | MME (0.49) | MMEACECPA1CPA2CPA4 | |
| SCHEMBL8450826 | 0.86 | MME (0.44) | MMEACECPA1CPA2CPA4 | |
| SCHEMBL8447142 | 0.85 | MME (0.47) | MMEACEUTS2RCTSBCYP3A4 | |
| SCHEMBL7565990 | 0.84 | MME (0.61) | MMEACEMTNR1AMTNR1BCPA1 | |
| SCHEMBL7566002 | 0.84 | MME (0.61) | MMEACEMTNR1AMTNR1BCPA1 | |
| SCHEMBL8446429 | 0.84 | MME (0.46) | MMEACECTSB | |
| SCHEMBL8449483 | 0.84 | MME (0.42) | MMEACEUTS2RMMP3 | |
| SCHEMBL8450113 | 0.83 | MME (0.43) | MMEACEUTS2RCTSBMMP3 | |
| SCHEMBL8447131 | 0.81 | MME (0.52) | MMEACEMTNR1AMTNR1BCPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |