Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.47 |
| ▸ | ACE | P12821 | 7/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.37 |
| ▸ | IL1RN | P18510 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446482 | 0.94 | MME (0.49) | MMEACEUTS2RBCHECTSB | |
| SCHEMBL8451265 | 0.89 | MME (0.49) | MMEACEERAP2ERAP1LNPEP | |
| SCHEMBL8449483 | 0.87 | MME (0.42) | MMEACEUTS2R | |
| SCHEMBL8447133 | 0.85 | MME (0.42) | MMEACEUTS2RCTSBCYP3A4 | |
| SCHEMBL8453065 | 0.84 | MME (0.51) | MMEACECTSB | |
| SCHEMBL8450113 | 0.83 | MME (0.43) | MMEACEUTS2RLNPEPCTSB | |
| SCHEMBL8449905 | 0.83 | MME (0.52) | MMEACE | |
| SCHEMBL8449504 | 0.82 | MME (0.40) | MMEACEUTS2R | |
| SCHEMBL7573678 | 0.82 | MME (0.71) | MMEACEBCHE | |
| SCHEMBL7573682 | 0.82 | MME (0.71) | MMEACEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |