Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.44 |
| ▸ | ACE | P12821 | 5/20 | 0.44 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | CPA2 | P48052 | 1/20 | 0.34 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453137 | 0.95 | MME (0.43) | MMEACEFDFT1CTSBNPC1 | |
| SCHEMBL8446429 | 0.95 | MME (0.46) | MMEACEFDFT1CTSBACACB | |
| SCHEMBL8446421 | 0.87 | MME (0.43) | MMEACEFDFT1CTSBACACB | |
| SCHEMBL8451834 | 0.87 | MME (0.44) | MMEACEFDFT1CTSBNPC1 | |
| SCHEMBL7567664 | 0.87 | MME (0.61) | MMEACECPA1 | |
| SCHEMBL7567672 | 0.87 | MME (0.61) | MMEACECPA1 | |
| SCHEMBL8446410 | 0.86 | MME (0.53) | MMEACEFDFT1CTSBCPA1 | |
| SCHEMBL8447133 | 0.86 | MME (0.42) | MMEACECTSBCPA1CPA2 | |
| SCHEMBL8453065 | 0.84 | MME (0.51) | MMEACEFDFT1CTSB | |
| SCHEMBL8450819 | 0.84 | MME (0.50) | MMEACECTSBCPA1CPA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |