Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP7 | P09237 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444918 | 0.94 | GRIN2B (0.39) | ALDH1A1GRIN2BGAATPSAB1TPSD1 | |
| SCHEMBL8448655 | 0.94 | GRIN2B (0.39) | ALDH1A1GRIN2BGAATPSAB1TPSD1 | |
| SCHEMBL7457369 | 0.89 | ALDH1A1 (0.39) | ALDH1A1GRIN2BGAAMMP1MMP3 | |
| SCHEMBL8444911 | 0.88 | GAA (0.41) | ALDH1A1GRIN2BGAATPSAB1TPSD1 | |
| SCHEMBL8448646 | 0.88 | GAA (0.41) | ALDH1A1GRIN2BGAATPSAB1TPSD1 | |
| SCHEMBL8536471 | 0.86 | ALDH1A1 (0.40) | ALDH1A1GRIN2BGAAMAPK1L3MBTL1 | |
| SCHEMBL8447430 | 0.85 | TPSAB1 (0.39) | ALDH1A1GRIN2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL8444908 | 0.85 | TPSAB1 (0.39) | ALDH1A1GRIN2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL8445627 | 0.84 | GRIN2B (0.39) | ALDH1A1GRIN2BGAAMAPK1L3MBTL1 | |
| SCHEMBL8445629 | 0.84 | GRIN2B (0.39) | ALDH1A1GRIN2BGAAMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977097-A | 1-methylcarbapenem derivatives | SANKYO COMPANY LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0900797-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1999-03-10 | — | — | EP | disclosed |