Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8447344 | 0.86 | ALDH1A1 (0.35) | ALDH1A1TDP1KMT2AUSP30 | |
| SCHEMBL8448555 | 0.83 | ALDH1A1 (0.39) | ALDH1A1RAB9ATDP1ATMUSP30 | |
| SCHEMBL8444895 | 0.83 | ALDH1A1 (0.39) | ALDH1A1RAB9ATDP1ATMUSP30 | |
| SCHEMBL8447148 | 0.82 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2RAB9APOLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8447212 | 0.81 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2RAB9APOLBL3MBTL1 | |
| SCHEMBL8447182 | 0.80 | USP30 (0.47) | ALDH1A1RAB9ATDP1ATMUSP30 | |
| SCHEMBL7454400 | 0.80 | USP30 (0.47) | ALDH1A1RAB9ATDP1ATMUSP30 | |
| Hydrochloric Acid SCHEMBL8448896 | 0.80 | IDO1 (0.38) | ALDH1A1SMN1; SMN2RAB9ALMNATDP1 | |
| Hydrochloric Acid SCHEMBL8447217 | 0.80 | TDP1 (0.38) | ALDH1A1RAB9ATDP1IDO1ATM | |
| SCHEMBL8445602 | 0.79 | CCR5 (0.41) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977097-A | 1-methylcarbapenem derivatives | SANKYO COMPANY LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0900797-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1999-03-10 | — | — | EP | disclosed |