Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 4/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | WRN | Q14191 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.33 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464159 | 0.92 | PRKCA (0.38) | ALDH1A1LMNANAAAPRKCAPRKCE | |
| SCHEMBL9464021 | 0.90 | ALDH1A1 (0.37) | ALDH1A1LMNANAAAPRKCAPRKCE | |
| SCHEMBL9463669 | 0.87 | NAAA (0.41) | ALDH1A1LMNANAAAPRKCAPRKCE | |
| SCHEMBL9463875 | 0.85 | NAAA (0.39) | ALDH1A1LMNANAAAPRKCAPRKCE | |
| SCHEMBL9463955 | 0.85 | NAAA (0.35) | ALDH1A1LMNANAAACYP1A2HPGD | |
| SCHEMBL9824006 | 0.85 | PRKCA (0.51) | ALDH1A1LMNANAAAPRKCAPRKCD | |
| SCHEMBL15281577 | 0.83 | ALDH1A1 (0.37) | ALDH1A1LMNANAAAPRKCAPRKCE | |
| SCHEMBL9463676 | 0.82 | NAAA (0.33) | ALDH1A1NAAACYP1A2HPGDCYP2C19 | |
| SCHEMBL9463663 | 0.82 | MAPK1 (0.38) | ALDH1A1NAAAPRKCACYP1A2HPGD | |
| SCHEMBL9463771 | 0.82 | NAAA (0.46) | ALDH1A1LMNANAAACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704445-B1 | Preparation of N-9 substituted guanine compounds | HOFFMANN LA ROCHE (CH) | 1999-04-21 | — | — | EP | disclosed |
| US-5565565-A | Preparation of N-9 substituted guanine compounds | SYNTEX (U.S.A.) INC. (US) | 1996-10-15 | — | — | US | disclosed |
| EP-0704445-A1 | Preparation of N-9 substituted guanine compounds | F. Hoffmann-La Roche AG (CH) | 1996-04-03 | — | — | EP | disclosed |
| US-5225590-A | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0187297-B1 | ALKOXY METHYL ETHER AND ALKOXY METHYL ESTER DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0187297-A2 | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-07-16 | — | — | EP | disclosed |