Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ODC1 | P11926 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3273673 | 0.86 | KMT2A (0.50) | MEN1KMT2APOLBTOP1ALDH1A1 | |
| SCHEMBL20349933 | 0.75 | MAPT (0.54) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL20349942 | 0.73 | MAPT (0.34) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL20349947 | 0.72 | ACHE (0.40) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL16317537 | 0.72 | NR3C1 (0.49) | MEN1KMT2APOLBTOP1ALDH1A1 | |
| SCHEMBL42727 | 0.70 | TOP1 (0.53) | MEN1KMT2APOLBTOP1ALDH1A1 | |
| SCHEMBL9343381 | 0.70 | TYMS (0.38) | MEN1KMT2APOLBTOP1ALDH1A1 | |
| SCHEMBL28148154 | 0.70 | CA1 (0.65) | MEN1KMT2ATOP1ALDH1A1KDM4E | |
| SCHEMBL30610021 | 0.69 | TOP1 (0.56) | MEN1KMT2APOLBTOP1ALDH1A1 | |
| SCHEMBL382674 | 0.69 | TOP1 (0.56) | MEN1KMT2APOLBTOP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557901-A | Efficient production method of pyrimidofuranone | 湖北有宜新材料科技有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-112174897-B | Preparation method of azoxystrobin intermediate | 广东石油化工学院 | 2021-08-03 | — | — | CN | disclosed |
| CN-112174897-A | Preparation method of azoxystrobin intermediate | 广东石油化工学院 | 2021-01-05 | — | — | CN | disclosed |
| EP-0940394-A1 | Chemical process | ZENECA LIMITED (GB) | 1999-09-08 | — | — | EP | disclosed |
| US-5847138-A | Chemical process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1998-12-08 | — | — | US | disclosed |
| EP-0592435-A1 | PROCESS FOR THE PREPARATION OF PYRIMIDINE COMPOUNDS | ZENECA LIMITED (GB) | 1994-04-20 | — | — | EP | disclosed |
| WO-1992008703-A1 | PROCESS FOR THE PREPARATION OF PYRIMIDINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-29 | — | — | WO | disclosed |