Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5827177 | 0.79 | RAB9A (0.41) | ALDH1A1TDP1MAPK1TSHRL3MBTL1 | |
| SCHEMBL3475707 | 0.78 | POLB (0.45) | ALDH1A1TDP1MAPK1L3MBTL1RECQL | |
| SCHEMBL5946492 | 0.77 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TDP1MAPK1TSHR | |
| SCHEMBL11207151 | 0.77 | CYP3A4 (0.38) | ALDH1A1CYP3A4TDP1MAPK1TSHR | |
| Diethanolamine SCHEMBL1043914 | 0.77 | MAPT (0.44) | ALDH1A1CYP3A4TDP1MAPK1TSHR | |
| Hydrochloric Acid SCHEMBL10901278 | 0.72 | TDP1 (0.50) | ALDH1A1CYP3A4TDP1MAPK1TSHR | |
| SCHEMBL6387872 | 0.72 | ALDH1A1 (0.41) | ALDH1A1CYP3A4TDP1MAPK1TSHR | |
| SCHEMBL6391940 | 0.72 | ALDH1A1 (0.41) | ALDH1A1CYP3A4TDP1MAPK1TSHR | |
| SCHEMBL6270360 | 0.71 | PRKCI (0.35) | ALDH1A1CYP3A4TDP1MAPK1TSHR | |
| SCHEMBL10565565 | 0.71 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TDP1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791352-B1 | Hair dyeing composition | GOLDWELL GMBH (DE) | 1999-09-08 | — | — | EP | claimed |
| US-4226595-A | Oxidation hair-coloring preparation based upon N,N-bis-(β-hydroxyethyl)-m-phenylenediamines | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1980-10-07 | — | — | US | claimed |
| US-4226595-A | Oxidation hair-coloring preparation based upon N,N-bis-(β-hydroxyethyl)-m-phenylenediamines | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1980-10-07 | — | — | US | disclosed |