Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5176324 | 0.90 | ALDH1A1 (0.41) | POLBKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10826961 | 0.82 | POLB (0.41) | POLBKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5827177 | 0.78 | RAB9A (0.41) | POLBKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8447828 | 0.78 | ALDH1A1 (0.39) | POLBKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL5366701 | 0.77 | KIF11 (0.42) | POLBKMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL3233448 | 0.77 | ALDH1A1 (0.42) | POLBKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11207151 | 0.77 | CYP3A4 (0.38) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL7906677 | 0.76 | ALDH1A1 (0.41) | POLBKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4823355 | 0.75 | ALDH1A1 (0.41) | POLBKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6666470 | 0.71 | ALDH1A1 (0.47) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7771734-B2 | Process to color and permanently restructure hair | WELLA AG (DE) | 2010-08-10 | — | — | US | claimed |
| EP-1655056-B1 | Process to colour and permanently restructure hair | WELLA AG (DE) | 2008-07-02 | — | — | EP | claimed |
| US-7273058-B2 | Dividing hair into individual strands and winding on curlers; prior to application on hair, mixing shaping component with dye component having keratin-reducing agent and 4,5-diaminopyrazole and/or aminophenol derivative(s); fixing, rinsing | WELLA AG (DE) | 2007-09-25 | — | — | US | claimed |
| EP-0858796-B2 | Oxidative hair dye | WELLA AG (DE) | 2007-04-11 | — | — | EP | claimed |
| US-20060096042-A1 | Process to color and permanently restructure hair | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2006-05-11 | — | — | US | claimed |
| EP-1655056-A1 | Process to colour and permanently restructure hair | Wella AG (DE) | 2006-05-10 | — | — | EP | claimed |
| EP-1287812-B1 | Method of simultaneously dyeing and permanent waving the hair | WELLA AG (DE) | 2006-04-05 | — | — | EP | claimed |
| US-6945254-B2 | Method for simultaneously dyeing and permanent shaping of hair | WELLA AKTIENGESELLSCHAFT (DE) | 2005-09-20 | — | — | US | claimed |
| US-20050086749-A1 | Method for simultaneously dyeing and permanent shaping of hair | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2005-04-28 | — | — | US | claimed |
| US-20030084518-A1 | Method for simultaneously dyeing and permanent shaping of hair | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-05-08 | — | — | US | claimed |
| EP-1287812-A2 | Method of simultaneously dyeing and permanent waving the hair | Wella Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | claimed |
| US-7771734-B2 | Process to color and permanently restructure hair | WELLA AG (DE) | 2010-08-10 | — | — | US | disclosed |
| EP-1655056-B1 | Process to colour and permanently restructure hair | WELLA AG (DE) | 2008-07-02 | — | — | EP | disclosed |
| US-7273058-B2 | Dividing hair into individual strands and winding on curlers; prior to application on hair, mixing shaping component with dye component having keratin-reducing agent and 4,5-diaminopyrazole and/or aminophenol derivative(s); fixing, rinsing | WELLA AG (DE) | 2007-09-25 | — | — | US | disclosed |
| EP-0858796-B2 | Oxidative hair dye | WELLA AG (DE) | 2007-04-11 | — | — | EP | disclosed |
| US-20030093867-A1 | Dyes for keratin fibres containing 1,3-diamino-4-heteroarylbenzene derivatives and novel 1,3-diamino-4-heteroarylbenzene derivatives | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-05-22 | — | — | US | disclosed |
| US-20030084518-A1 | Method for simultaneously dyeing and permanent shaping of hair | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-05-08 | — | — | US | disclosed |
| EP-1287812-A2 | Method of simultaneously dyeing and permanent waving the hair | Wella Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| EP-0858796-B1 | Oxidative hair dye | WELLA AG (DE) | 2003-02-26 | — | — | EP | disclosed |
| EP-0858796-A2 | Oxidative hair dye | Wella Aktiengesellschaft (DE) | 1998-08-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050086749-A1 | Method for simultaneously dyeing and permanent shaping of hair | KRT18, KDM5B, KDM5C | POLB 409/4885KMT2A 446/4885MEN1 3790/4885 |
| US-20030093867-A1 | Dyes for keratin fibres containing 1,3-diamino-4-heteroarylbenzene derivatives and novel 1,3-diamino-4-heteroarylbenzene derivatives | KRT18, DSP, TUBB4B | POLB 706/4885KMT2A 1043/4885MEN1 3993/4885 |
| US-20030084518-A1 | Method for simultaneously dyeing and permanent shaping of hair | KRT18, KMO, TYR | POLB 540/4885KMT2A 526/4885MEN1 4747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.