Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Etiracetam. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CA3 | P07451 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
| ▸ | CA6 | P23280 | 1/20 | 0.65 |
| ▸ | CA5A | P35218 | 1/20 | 0.65 |
| ▸ | CA7 | P43166 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.65 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levetiracetam SCHEMBL118843 | 0.81 | LMNA (1.00) | LMNACA12CA1CA2CA3 | |
| Levitiracetam SCHEMBL61493 | 0.81 | LMNA (1.00) | LMNACA12CA1CA2CA3 | |
| Levetiracetam SCHEMBL5072485 | 0.81 | LMNA (1.00) | LMNACA12CA1CA2CA3 | |
| Etiracetam SCHEMBL373194 | 0.81 | LMNA (1.00) | LMNACA12CA1CA2CA3 | |
| Etiracetam SCHEMBL28457423 | 0.79 | LMNA (0.97) | LMNACA12CA1CA2CA3 | |
| Etiracetam SCHEMBL22031970 | 0.79 | LMNA (0.97) | LMNACA12CA1CA2CA3 | |
| Levetiracetam SCHEMBL17372720 | 0.79 | LMNA (0.97) | LMNACA12CA1CA2CA3 | |
| Etiracetam SCHEMBL28026798 | 0.79 | LMNA (0.97) | LMNACA12CA1CA2CA3 | |
| Oxiracetam SCHEMBL28014647 | 0.78 | APEX1 (0.87) | APEX1BLMTSHR | |
| Oxiracetam SCHEMBL2596758 | 0.78 | APEX1 (1.00) | APEX1BLMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804239-B1 | ANTI-STRESS, ANTI-IMPAIRMENT AND ANTI-AGING DRUG AND PROCESS FOR MANUFACTURING THEREOF | RIGA DAN (RO) | 1999-09-15 | — | — | EP | disclosed |