Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.62 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448322 | 1.00 | POLB (0.62) | POLBCTDSP1PLK1THRBL3MBTL1 | |
| SCHEMBL8448673 | 0.90 | PLK1 (0.53) | POLBCTDSP1PLK1THRBL3MBTL1 | |
| SCHEMBL7801088 | 0.90 | PLK1 (0.53) | POLBCTDSP1PLK1THRBL3MBTL1 | |
| SCHEMBL9022670 | 0.90 | PLK1 (0.53) | POLBCTDSP1PLK1THRBL3MBTL1 | |
| SCHEMBL415439 | 0.83 | POLB (0.62) | POLBCTDSP1PLK1L3MBTL1TAAR1 | |
| SCHEMBL9225095 | 0.82 | ESR1 (0.56) | POLBCTDSP1PLK1THRBL3MBTL1 | |
| SCHEMBL11957409 | 0.82 | GAA (0.55) | POLBCTDSP1PLK1THRBL3MBTL1 | |
| SCHEMBL9399014 | 0.82 | PLK1 (0.50) | POLBCTDSP1PLK1THRBL3MBTL1 | |
| SCHEMBL9220484 | 0.82 | PLK1 (0.50) | POLBCTDSP1PLK1THRBL3MBTL1 | |
| SCHEMBL9399023 | 0.82 | PLK1 (0.50) | POLBCTDSP1PLK1THRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109762576-B | Liquid crystal compound, liquid crystal composition and application thereof | 武汉轻工大学 | 2021-06-29 | — | — | CN | disclosed |
| US-5914071-A | Difluoroethylene compounds and liquid crystal compositions containing them | ASAHI GLASS COMPANY LTD. (JP) | 1999-06-22 | — | — | US | disclosed |
| US-5663463-A | Difluoroethylene compounds and liquid crystal compositions containing them | ASAHI GLASS COMPANY LTD. (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0560382-B1 | Difluoroethylene compounds and liquid crystal compositions containing them | ASAHI GLASS CO LTD (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5516949-A | LOW VISCOSITY AND PHOTOSTABLE | ASAHI GLASS COMPANY LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| EP-0560382-A1 | Difluoroethylene compounds and liquid crystal compositions containing them | ASAHI GLASS COMPANY LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |